Search Result

Search Results for " protease cysteine 2 "

Targets

Compounds

312

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10924	Cysteine protease inhibitor-2		Cysteine Protease
	Cysteine protease inhibitor 2 is a cysteine protease inhibitor. Cysteine protease inhibitor 2 inhibited DCT116 and PC3 cells with GI50 values of 6.5 μM and 4.4 μM, respectively.		Cysteine Protease
T7451	2-Cyanopyrimidine	2-cyano-Pyrimidine	Cysteine Protease
	2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)		Cysteine Protease
T9458	PF-00835231		SARS-CoV
	PF-00835231 is a CoV-2 cysteine 3C-like protease (3CLpro) inhibitor, with IC50s of 0.27 nM and 4 nM for SARS CoV-2 and SARS CoV-1 3CLpro, respectively.PF-00835231 is the active compound of the first anti-3CLpro regimen i...		SARS-CoV
T80542	Z-Leu-Leu-Leu-fluoromethyl ketone	Z-LLL-FMK
	Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) functions as a cysteine protease inhibitor and has been shown to impede SARS infection. Furthermore, it affords protection to mice when challenged with T. crassiceps [1] [2].
T63537	SARS-CoV-2 3CLpro-IN-1
	SARS-CoV-2 3CLpro-IN-1 (Compound 14c) is a highly potent inhibitor specifically designed to target and inhibit the activity of SARS-CoV-2 3CL pro, which is a cysteine-protease found in the main coronaviruses. This partic...
T63760	3CPLro-IN-2
	3CPLro-IN-2 is a potent, orally active inhibitor of SARS-CoV-2 3CLpro (IC50: 1.55 μM, Ki: 6.09 μM). 3-Chymotrypsin-like cysteine protease (3CLpro) is an essential protein for viral replication and is a potential drug tar...
T64159	Cathepsin K inhibitor 2
	Cathepsin K inhibitor 2 is a potent inhibitor of cathepsin K. Cathepsin K (Cat K) is a cysteine protease expressed under the control of the CTSK gene, which is closely related to osteoporosis and hydrolyses collagen. cat...
T62479	3CPLro-IN-1
	3CPLro-IN-1 (compound A17) is a potent, orally active inhibitor of SARS-CoV-2 3CLpro (IC50: 5.65 μM). 3-Chymotrypsin-like cysteine protease (3CLpro), a protein essential for viral replication, is an attractive drug targe...
T78119	Z-L(D-Val)G-CHN2		HSV
	Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase. This tripeptide derivative emulates a segment of the human cysteine proteinase-binding center and ...		HSV
T35802	ML-345
	Insulin-degrading enzyme (IDE) is a thiol-sensitive zinc-metallopeptidase that acts as the major insulin-degrading protease in vivo, mediating the termination of insulin signaling. [1] In addition to regulating insulin a...
T36668	Geranylgeranoic Acid
	Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not...

Compounds

Cysteine protease inhibitor-2

T10924

Synonym:

Target: Cysteine Protease

2-Cyanopyrimidine

T7451

Synonym: 2-cyano-Pyrimidine

Target: Cysteine Protease

Z-Leu-Leu-Leu-fluoromethyl ketone

T80542

Synonym: Z-LLL-FMK

Target:

SARS-CoV-2 3CLpro-IN-1

Cathepsin K inhibitor 2

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-01250	ATG4A Protein, Human, Recombinant (His)	Human	E. coli
	Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and b...
TMPJ-01278	SENP8 Protein, Human, Recombinant (His)	Human	E. coli
	Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins ...
TMPY-00767	Cystatin C Protein, Human, Recombinant (His)	Human	HEK293
	Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPJ-00025	CST7 Protein, Human, Recombinant (His)	Human	Human Cells
	CST7 is a secreted protein and primarily expressed in peripheral blood cells and spleen.It is belongs to the cystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. S...
TMPH-02342	Collagenase Protein, Hypoderma lineatum, Recombinant (His & Myc)	Hypoderma lineatum	E. coli
	This enzyme is a serine protease capable of degrading the native triple helix of collagen. Also cleaves the B chain of insulin at the 15-Leu-\|-Try-16 and 22-Arg-\|-Gly-23 bonds. Hydrolyzes casein, but not Px-Pro-Leu-Gly-P...
TMPJ-00929	Serpin B3 Protein, Human, Recombinant (N-His)	Human	E. coli
	Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ...
TMPJ-00928	Serpin B3 Protein, Human, Recombinant (C-His)	Human	Human Cells
	Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in ...
TMPY-02845	CST9L Protein, Human, Recombinant (hFc)	Human	HEK293
	Testatin is a member of the Cystatin family. Cystatins comprise genes that all show expression patterns that are strikingly restricted to reproductive tissue. Cystatins are a family of cysteine protease inhibitors with h...
TMPY-01645	Cystatin SA Protein, Human, Recombinant (His)	Human	HEK293
	Cystatin-SA, also known as Cystatin-2, Cystatin-S5 and CST2, is a secreted protein which belongs to thecystatin family. Cystatin-2 / CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (...
TMPY-00768	CST6 Protein, Human, Recombinant (His)	Human	HEK293
	Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing ...
TMPJ-01256	Caspase-10 Protein, Human, Recombinant (His)	Human	E. coli
	Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPY-02665	CST6 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing ...
TMPY-01644	Cystatin S Protein, Human, Recombinant (His)	Human	HEK293
	Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual sali...
TMPY-01368	Cystatin F/CST7 Protein, Human, Recombinant (His)	Human	HEK293
	The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
TMPY-00769	Cystatin F/CST7 Protein, Human, Recombinant (hFc)	Human	HEK293
	The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
TMPY-02856	Cystatin F/CST7 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
TMPY-00770	Cystatin F/CST7 Protein, Human, Recombinant	Human	HEK293
	The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-li...
TMPY-00640	Cystatin C Protein, Human, Recombinant	Human	HEK293
	Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-02056	Cystatin C Protein, Rat, Recombinant (His)	Rat	HEK293
	Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-01370	Cystatin C Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293
	Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149)	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli.
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-02011	CD96 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00871	LAYN Protein, Human, Recombinant (hFc)	Human	HEK293
	Layilin recently characterized as a 55 kDa transmembrane protein with homology to C-type lectins, is present in numerous cell lines and tissue extracts. As one of the adaptor proteins, talin mediates the interactions bet...
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00748	Nectin-2 Protein, Human, Recombinant	Human	HEK293
	Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein a...
TMPY-00005	FGF-8a Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-02358	CD98 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His)	Human	HEK293
	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His)	Human	HEK293
	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	Human Cells
	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-04356	GSK3B Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc)	Human	HEK293
	CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-05586	CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPY-01199	CD74 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05427	CD19 Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04844	BTN3A1 Protein, Human, Recombinant (His)	Human	HEK293
	BTN3A1 has the structure of a type I receptor of the Ig superfamily and is part of a family of seven BTN receptors encoded by genes in the MHC. BTN molecules are composed of two Ig domains (IgV, IgC2), a single transmemb...
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 cells.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinit...
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-01935	C-Kit Protein, Human, Recombinant (His)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-02096	TACI Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF...
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00751	TrkB Protein, Human, Recombinant (His)	Human	HEK293
	TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
------------------------ More ------------------------